Listar por autor "Fernández Celis, Amaya"
Mostrando ítems 1-5 de 5
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Characterization of the sex-specific pattern of angiogenesis and lymphangiogenesis in aortic stenosis
Matilla Cuenca, Lara; Martín Núñez, Ernesto; Garaikoetxea, Mattie; Navarro, Adela; Vico, Julieta Anabela; Arrieta Paniagua, Vanessa; García Peña, Amaia; Fernández Celis, Amaya; Gaínza Calleja, Alicia; Álvarez, Virginia; Sádaba Sagredo, Rafael; López Andrés, Natalia; Jover, Eva (Frontiers Media, 2022) Artículo / ArtikuluaObjective: We aim to analyze sex-related differences in angiogenesis and lymphangiogenesis in aortic valves (AVs) and valve interstitial cells (VICs) from aortic stenosis (AS) patients. Approach and Results: Totally 230 ... -
Influence of diabetes mellitus on the pathological profile of aortic stenosis: a sex-based approach
Martín Núñez, Ernesto; Goñi Olóriz, Miriam; Matilla Cuenca, Lara; Garaikoetxea Zubillaga, Mattie; Mourino-Álvarez, Laura; Navarro, Adela; Fernández Celis, Amaya; Tamayo Rodríguez, Ibai; Gaínza Calleja, Alicia; Álvarez, Virginia; Sádaba Sagredo, Rafael; Barderas, María G.; Jover, Eva; López Andrés, Natalia (Springer Nature, 2023) Artículo / ArtikuluaBackground: Diabetes mellitus (DM) accelerates the progression of aortic stenosis (AS), but how their underlying molecular mechanisms interact is not clear. Moreover, whether DM contributes to clinically relevant sex-differences ... -
Sex-dependent expression of neutrophil gelatinase-associated lipocalin in aortic stenosis
Jover, Eva; Matilla Cuenca, Lara; Martín Núñez, Ernesto; Garaikoetxea Zubillaga, Mattie; Navarro, Adela; Fernández Celis, Amaya; Gaínza Calleja, Alicia; Arrieta Paniagua, Vanessa; García Peña, Amaia; Álvarez, Virginia; Sádaba Sagredo, Rafael; Jaisser, Frederic; López Andrés, Natalia (BMC, 2022) Artículo / ArtikuluaBackground: Accumulating evidence suggest the existence of sex-related differences in the pathogenesis of aortic stenosis (AS) with inflammation, oxidative stress, fibrosis and calcification being over-represented in men. ... -
Soluble ST2 as a new oxidative stress and inflammation marker in metabolic syndrome
Roy, Ignacio; Jover, Eva; Matilla Cuenca, Lara; Álvarez, Virginia; Fernández Celis, Amaya; Beunza, Maite; Escribano, Elena; Gaínza Calleja, Alicia; Sádaba Sagredo, Rafael; López Andrés, Natalia (MDPI, 2023) Artículo / ArtikuluaBackground: Metabolic syndrome (MS) is a complex and prevalent disorder. Oxidative stress and inflammation might contribute to the progression of MS. Soluble ST2 (sST2) is an attractive and druggable molecule that sits at ... -
Targeting fatty acid-binding protein 4 improves pathologic features of aortic stenosis
Garaikoetxea, Mattie; Martín Núñez, Ernesto; Navarro, Adela; Matilla Cuenca, Lara; Fernández Celis, Amaya; Arrieta Paniagua, Vanessa; García Peña, Amaia; Gaínza Calleja, Alicia; Álvarez, Virginia; Sádaba Sagredo, Rafael; Jover, Eva; López Andrés, Natalia (MDPI, 2022) Artículo / ArtikuluaAortic stenosis (AS) is a fibrocalcific disease of the aortic valves (AVs). Sex-differences in AS pathophysiology have recently been described. High levels of fatty acid-binding protein 4 (FAPB4) in atherosclerotic plaques ...